陈士林
陈士林， 男， 中国医学科学院学部委员1，俄罗斯工程院外籍院士2、国际欧亚科学院院士3、俄罗斯自然科学院外籍院士4。现任成都中医药大学首席教授5、中国中医科学院首席研究员6、香港浸会大学荣誉教授、兼任世界卫生组织传统医学合作中心主任7、 CGCM（中药全球化联盟）副主席，中国质量协会中药分会会长等8。曾任中国医学科学院药用植物研究所所长9、中国中医科学院中药研究所所长10、香港理工大学客座教授等、并在英国皇家植物园丘园接受专业培训、哈佛医学院Mclean医院做访问学者等11。兼任日本东京药科大学客座教授、美国药典传统中药咨询组委员等。担任APSB，Chinese Medicine，《药学学报》等刊副主编12。
2020年5月，获得第二届全国创新争先奖章13。
2023年11月22日，当选2023年中国工程院院士14。
基本信息
科研成就
陈士林创建了基于ITS2的中草药DNA条形码鉴定方法体系，完成专著《中国药典中药材DNA条形码标准序列》，从基因层面解决中草药物种真伪鉴定的难题，被评为2016中国十大医学进展20；
通过全基因组解析提出灵芝为首个中药基原药用模式真菌，被Nature China 选为中国最佳研究亮点推介21；
完成并发表人参22、丹参23、赤芝24、菊花25、卷柏26、穿心莲27、紫芝28、紫苏29、黄连30、红豆杉31、黄花蒿32等全基因组图谱和相关组学研究，成功培育并获批11个中药材新品种证书或良种证书，提出并主编《本草基因组学》学科由科学出版社出版，列为全国高等医药院校规划教材，出版《药用植物分子遗传学》，奠定药用植物分子遗传学基础33。
完成并编著《中国中药材产地生态适宜性数值区划》，避免中药材盲目引种栽培34；
主要论文
1. Sun, S., Shen, X., Li, Y., Li, Y., Wang, S., Li, R., Zhang, H., Shen, G., Guo, B., Wei, J., Xu, J., St-Pierre, B., Chen, S., & Sun, C. Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism. Nature plants. 2023. 9(1), 179–190.
2. Chen, S., Xu, J., Liu, C., Zhu, Y., Nelson, D. R., Zhou, S., Li, C., Wang, L., Guo, X., Sun, Y., Luo, H., Li, Y., Song, J., Henrissat, B., Levasseur, A., Qian, J., Li, J., Luo, X., Shi, L., He, L., … Sun, C. Genome sequence of the model medicinal mushroom Ganoderma lucidum. Nature Communications. 2012, 3, 913.
3. Yujun, Zhang., Qi, Shen., Liang, Leng., Dong, Zhang., Sha, Chen., Yuhua, Shi., Zemin, Ning., & Shilin, Chen. Incipient diploidization of the medicinal plant Perilla within 10,000 years，Nature Communications. 2021, 12(1):5508.
4. Liu Y, Wang B, Shu S, Li Z, Song C, Liu D, Niu Y, Liu J, Zhang J, Liu H, Hu Z, Huang B, Liu X, Liu W, Jiang L, Alami MM, Zhou Y, Ma Y, He X, Yang Y, Zhang T, Hu H, Barker MS, Chen S, Wang X, Nie J. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nature Communications. 2021, 12(1):3276.
5. Chen S., Song, J., Sun, C., Xu, J., Zhu, Y., Verpoorte, R., Fan, T.-P*. Herbal genomics: Examining the biology of traditional medicines. Science. 2015,347(6219), S27-S29.
6. China Plant BOL Group, Li DZ, Gao LM, Li HT, Wang H, Ge XJ, Liu JQ, Chen ZD, Zhou SL, Chen SL, Yang JB, Fu CX, Zeng CX, Yan HF, Zhu YJ, Sun YS, Chen SY, Zhao L, Wang K, Yang T, Duan GW. Comparative analysis of a large dataset indicates that internal transcribed spacer (ITS) should be incorporated into the core barcode for seed plants. PNAS. 2011,108:19641-19646.
7. Liao B, Shen X, Xiang L, Guo S, Chen S, Meng Y, Liang Y, Ding D, Bai J, Zhang D, Czechowski T, Li Y, Yao H, Ma T, Howard C, Sun C, Liu H, Liu J, Pei J, Gao J, Wang J, Qiu X, Huang Z, Li H, Yuan L, Wei J, Graham I, Xu J, Zhang B, Chen S*. Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield. Molecular plant. 2022, 5(8):1310-1328.
8. Song, C; Liu, Y; Song, A; Dong, G; Zhao, H; Sun, W; Ramakrishnan, Shyam; Wang, Y; Wang, S; Li, T; Niu, Y; Jiang, J; Dong, B; Xia, Y; Chen, S; Hu, Z; Chen, F; Chen, Shilin, The Chrysanthemum nankingense genome provides insights into the evolution and diversification of chrysanthemum flowers and medicinal traits. Molecular plant. 2018, 11(12): 1482-1491.
9. Chen, S., Yin, X., Han, J., Sun, W., Yao, H., Song, J., & Li, X. DNA barcoding in herbal medicine: retrospective and prospective. Journal of Pharmaceutical Analysis. 2023.
10. Chen, X., Yang, Z., Xu, Y., Liu, Z., Liu, Y., Dai, Y., & Chen, S. Progress and prediction in multicomponent quantification of complex systems with practical LC-UV methods. Journal of Pharmaceutical Analysis, 2022.
11. Guo M, Pang X, Xu Y, Jiang W, Liao B, Yu J, Xu J, Song J, Chen S. Plastid genome data provide new insights into the phylogeny and evolution of the genus Epimedium. Journal of Advanced Research. 2021, 36:175-185.
12. Xu J, Chu Y, Liao B, Xiao S, Yin Q, Bai R, Su H, Dong L, Li X, Qian J, Zhang J, Zhang Y, Zhang X, Wu M, Zhang J, Li G, Zhang L, Chang Z, Zhang Y, Jia Z, Liu Z, Daniel Afreh, Ruth Nahurira8, Zhang L, Cheng R, Zhu Y, Zhu G, Rao W, Zhou C, Qiao L, Huang Z, Cheng Yung-Chi, Chen Shilin, Panax ginseng genome examination for ginsenoside biosynthesis. GigaScience. 2017, 6(11):1-15.
13. Chen, S., Li, Z., Zhang, S., Zhou, Y., Xiao, X., Cui, P., Xu, B., Zhao, Q., Kong, S., & Dai, Y. (2022). Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses. Acta Pharmaceutica Sinica B, 12(11).