• 1.摘要
  • 2.基本介绍
  • 3.研究内容
  • 4.主要研究论文
  • 5.获奖荣誉

李娟

49
四川大学生命科学院副教授

李娟,(四川大学生命科学院副教授)

研究内容:“下丘脑-垂体-靶器官”作用通路,是调节动物生长发育的主要途径。李娟博士目前在国家自然科学基金, 国家高科技研究计划(863),转基因新品种培育专项支持下,以家鸡为研究模型,关注“下丘脑-垂体-卵巢”通路,围绕催乳素生成释放机制,卵泡发育机制开展受体功能鉴定与基因网络调控解析。

基本介绍

学习与工作经历:

1990-1994:四川大学,理学学士

1994-1997:四川大学,理学硕士

1997-1999:成都生物制品研究所,实习研究员

1999-2003:香港大学动物学系,理学博士

2004-2006:香港大学动物学系, 博士后

2006-现在:四川大学生命科学院

研究内容

“下丘脑-垂体-靶器官”作用通路,是调节动物生长发育的主要途径。李娟博士目前在国家自然科学基金, 国家高科技研究计划(863),转基因新品种培育专项支持下,以家鸡为研究模型,关注“下丘脑-垂体-卵巢”通路,围绕催乳素生成释放机制,卵泡发育机制开展受体功能鉴定与基因网络调控解析。

主要研究论文

1. Huang G, Li Juan*, Fu H, Yan Z, Bu G, He X, Wang Y. Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Domestic Animal Endocrinology (on line: DOI:10-1016/ j.domaniend. 2012.01.005), 2012 (* 通迅作者)

2. Wang Y, Huang G, Li Juan, Meng F, He X. Leung F.C . Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology, 348: 270-280, 2012

3. Wang Y, Wang CY, Wu Y, Huang G, Li Juan, Leung F C. Identification of the Receptors for Prolactin-releasing Peptide (PrRP) and Carassius RFamide Peptide (C-RFa) in Chickens. Endocrinology 153, p1-14 (DOI: 10.1210/en.2011-1719), 2012

4. Wang Y, Li Juan, Kwok AHY, Ge W & Lueng FC. A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: Cloning and Characterization of its tissue expression. General and Comparative Endocrinology 166: 200-210, 2010

5. Wang Y, Li Juan, C. Wang CY, Kwok AHY, Zhang X & Leung FC. Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domestic Animal Endocrinology 38: 13-31, 2010

6. Wang J, Wang Y, Li X, Li Juan* and Leung FC. Cloning, tissue distribution and functional characterization of chicken glucagon receptor. Poultry Science 87:2678-2688, 2008 (*通讯作者)

7. Li Juan, Wang X, and Leung FC. The intragenomic polymorphism of a partially inverted repeat (PIR) in Gallus gallus domesticus, potential role of inverted repeats in satellite DNAs evolution. Gene 387:118-125, 2007

8. Wang Y, Li Juan, Wang CY, Kwok AH, and Leung FC. Epidermal growth factor receptor (EGFR) ligands in the chicken ovary: evidence for heparin-binding EGF-like growth factor (HB-EGF) as a potential oocyte-derived signal to control granulosa cell proliferation and HB-EGF and kit ligand expression. Endocrinology 148:3426-3440, 2007