人物生平

郑毅男，男，1945年出生，汉族，中共党员，民盟盟员，吉林省第九届人大代表，留日医学博士，吉林农业大学中药材学院教授，作物栽培学与耕作学学科博士生导师。吉林省特产学会副理事长，中国人参学会常务理事，中国植物学会药用植物及中药专业委员会委员，国家中医药管理局“中药学”重点学科学科带头人。

主要成就

先后为硕士、博士研究生主讲《中药炮制学》、《天然药物化学》等多门课程；在科学研究上，一直从事中药方面研究，尤其在人参加工理论方面颇有见地，发现红参加工是遵循梅拉德反应的原理；同时发现人参中具有广泛生理活性的AFG，是首次自人参中分离得到的新天然化合物，其含量超过人参总皂苷，为人参的评价和临床应用提供了新的理论依据。曾先后主持国家、部省级科研项目15项，获得多项科研成果，其中获省科学技术进步二等奖1项；获长春市科技进步二等奖1项，其中“人参非皂苷抗衰老保健品开发研究”经鉴定达到国际领先，已经申请“人参次级皂苷脂肪酸酯合成及其应用”、“人参果提取物的制备方法及治疗糖尿病的药物用途”等发明专利2项；多年来，发表学术论文100余篇，其中SCI收录9篇；出版科技著作2部。主要从事保健食品和癌症辅助治疗药物的研究，现正主持教育部、科技厅以及横向联合等3项在研基金项目。

[1] Zheng Yi-nan, Zhang Jing, Han Li-kun, Sekiya Keizo, Kimura Yoshiyuki, Okuda Hiromichi. Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. Yakugaku Zasshi. 2005, 125(12):1005-1008.

[2] Han Li-kun, Nose Rumiko, Li Wei, Gong Xiao-jie, Zheng Yi-nan, Yoshikawa Masayuki, Koike Kazuo, Nikaido T amotsu, Okuda Hiromichi, Kimura Yoshiyuki. Reduction of fat storage in mice fed a high-fat diet long term by treatment with saponins prepared from Kochia scoparia fruit. Phytother Res, 2006, 20(10):877-882.

[3] Xiang Li, Zheng Yinan, Isabel Sattler and Wenhan Lin，Griseusin C, and novel quinone derivative from a marine-derived fungus Penicillium sp. Arch Pharm Res. 2006, 29(11): 942-945.

[4] Li Xiang, Zheng Yi-nan Lin Wen-han, Sattler Isabel. A New Vriginae Butanolide from Streptomyces sp. Chin Chem Lett, 2006, 17(11):1466-1468.

[5] Li Xiang; Li Min-yi; Zheng Yi-nan; Lin Wen-han. Structure Elucidation of Taraxerone Isolated from Mangrove Excoecaria Agallocha. Chinese Journal of Magnetic Resonance, 2006, 23(4):451-456.

[6] Li Wei, Xiang Lan, Zhang Jing, Zheng Yinan, Han Likun, Saitoc Masato. A New triterpenoid saponin from the roots of Platycodon grandiflorum. Chin Chem Lett, 2007, 18(3):306-308.

[7] Lei Jun, Li Xiang, Gong Xiao-jie, Zheng Yi-nan. Isolation, synthesis and structures of cytotoxic ginsenoside derivatives. Molecules, 2007, 12(9):2140-2150.

[8] Xu Chun-lian, Zheng Yi-nan, Yang Xiu-wei, Li Xiang-gao, Li Xiang, Chen Quan-cheng. Raddeanalin, a new flavonoid glycoside from the leaves of Salix raddeana Laksh. J Asian Nat Prod Res, 2007, 9(3-5):415-419.

[9] Li Xiang, Lei Jun, Zheng Yi-nan, Sattler Isabel, Lin Wen-han. New ent-Isopimarane Diterpene from Mangrove Excoecaria agallocha L. Chem Res Chinese U, 2007, 23(5):541-543.

[10] Han LK, Morimoto C, Zheng YN, Li Wei, Asami E, Okuda H, Saito M. Effects of Zingerone on Fat Storage in Ovariectomized Rats. YAKUGAKU ZASSHI, 2008, 128(8):1195-1201.

[11] Hu Jiang-ning, Zhu Xue-mei, Han Li-kun, Saito Masato, Sun Yin-shi, Yoshikawa Masayuki, Kimura Yoshiyuki, Zheng Yi-nan. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae). Chem Pharm Bull, 2008, 56(1):12-16.

[12] Li Xiang, Liu Zhi, Zhang Xin-feng, Wang Li-juan, Zheng Yi-nan, Yuan Chang-chun, Sun Guang-zhi. Isolation and characterization of phenolic compounds from the leaves of Salix matsudana. Molecules, 2008, 13(8):1530-1537.

[13] Hu Jiang-ning, Zhu Xun-mei, Lee Ki-Teak, Zheng Yi-nan, Li wei, Han Li-kun, Fang Zhe-ming, Gu Li-juan, Sun Bai-sheng, Wang Chuan-yan, Sung Chang-keun. Optimization of ginsenosides hydrolyzing beta-glucosidase production from Aspergillus niger using response surface methodology. Biol Pharm Bull, 2008, 31(10):1870-1874

[14] Liu Wen-cong, Zheng Yi-nan, Masato Saito, Wang Hai-min, Yoshiyuki Kimura, Ling Ming-song, Feng Yi-xiong. Saponins from stems and leaves of Panax quinquefolium prevented high fat diet-induced obesity in mice. Phytomedicine, 2008, 15(12), 1140-11452.

[15] Cao Da-peng, Zheng Yi-nan, Qin Lu-ping, Han T, Zhang H, Rahman K, Zhang Qiao-yan. Curculigo orchioides, a traditional Chinese medicinal plant, prevents bone loss in ovariectomized rats. Maturitas, 2008, 59(4):373-380.