个人简介

樊小龙 ： 是2009年北京师范大学从国外重点引进的生理学科学术带头人。于1992年获德国Greifswald大学人类遗传学博士学位；1992－1997为德国Greifswald大学免疫学和移植医学研究所博士后，从事细菌感染生物学研究; 从1997至今 一直在瑞典隆德大学医学院工作，历任助教授、副教授职务；2002年起担任独立研究小组负责人和博士生第一导师。获多项瑞典国家级独立课题以及多个非瑞典国际基金会的资助。长期从事血液干细胞、肿瘤生理学及病毒与诉诸关系等研究，取得了一系列科研成就，并获得若干重大原始性创新性工作成果。

资助机构：Swedish Cancer Foundation 项目名称: 1) Signaling based characterization and manipulation of human candidate hematopoietic stem cells and leukemic stem cells (2002 to 2008). 2). Role of stem and progenitor cells in cancer initiation and progression (from 2009) 资助金额：3百万克郎

资助机构：Swedish Research Council 项目名称：Development of adenoviral vectors for intrinsic gene expression based isolation and ex vivo expansion of human candidate hematopoietic stem cells. 起止年月2008-01-01 to 2010-12-31 资助金额 1.275百万克郎

资助机构：Swedish Pediatric Cancer Foundation 项目名称：Clarifying lineage involvement mechanisms and development of anti-MENIN based therapy for MLL fusion gene related childhood leukemia 起止年月2005-01-01 to 2009-12-31 资助金额 1.65百万克郎

代表性论文

（2006－2009）1) Marcus Järås, Petra Johnels, Helena Ågerstam, Carin Lassen, Marianne Rissler, Patrik Edén, Jörg Cammenga, Tor Olofsson, Ole Weis Bjerrum, Johan Richter, Xiaolong Fan, and Thoas Fioretos: Expression of P190 or P210 BCR/ABL1 in human CD34+ cells induce similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage. Experimental Hematology 37:367-75, 2009. 2) Johan Rebetz, Dongping Tian, Annette Persson, Bengt Widegren, Leif G. Salford, Elisabet Englund, David Gisselsson and Xiaolong Fan. Glial progenitor-like phenotype in low-grade gliomas and enhanced CD133-expression and neuronal lineage differentiation in high-grade gliomas. PLoS ONE 3:e1936, 2008. 3) Changqing Su, Manli Na, Jie Chen, Xinghua Wang, Yongjing Liu, Weiguo Wang, Qi Zhang, Linfang Li, Ju Long, Xinyuan Liu, Mengchao Wu, Xiaolong Fan, and Qijun Qian: Gene-Viral Cancer Therapy Using Dual-Regulated Oncolytic Adenovirus with Anti-angiogenesis Gene for Increased Efficacy. Molecular Cancer Research 6:568-575, 2008. 4) Peng Zhao, Cunzu Wang, Zheng Fu, Yongping You, Yunxiang Cheng, Xiaoming Lu, Ailin Lu, Ning Liu, Peiyu Pu, Chunsheng Kang, Leif G. Salford, and Xiaolong Fan. Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacities in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner. Internal Journal of Oncology 31:361-368,2007. 5) Christine Glanz, Johan Rebetz, Ylva Stewénius, Annette Persson, Elisabet Englund, Leif G Salford, Bengt Widegren, Xiaolong Fan*, David Gisselsson*: Glioblastoma multiforme-maintaining cells characterized by reduced genomic instability, preserved telomere integrity, and heterogeneous cell population generation capacity. Neuropathology and Applied Neurobiology 33:440-454, 2007 *: equal contribution. 6) Yong Wang, Shizhong Wang, Yongyi Bao, Cheng Ni, Naifu Guan, Jianzhong Zhao, Leif G. Salford, Bengt Widegren and Xiaolong Fan: Coxsackievirus and adenovirus receptor expression in non-malignant lung tissues and clinical lung cancer. Journal of Molecular Histology, 37:153-60, 2006 7) Marcus Järås, Anna Edqvist, Johan Rebetz, Leif G. Salford, Bengt Widegren and Xiaolong Fan: Human Short-term Repopulating Cells Have Enhanced Telomerase Reverse Transcriptase Expression. Blood 108:1084-1091, 2006. 8) Edqvist A, Rebetz J, Järås M, Rydelius A, Skagerberg G, Salford LG, Widegren B, and Fan X: Detection of cell cycle-and differentiation-stage dependent human telomerase reverse transcriptase expression in single living cancer cells. Molecular Therapy 14:139-148, 2006.