程国锋
程国锋,男,1974年出生,中国动物卫生与流行病学中心上海分中心和中国农业科学院上海兽医研究所研究员,博士生导师,课题组长。主要研究人兽共患寄生虫的生长、发育分子机理及新型防控技术。主要以血吸虫为主要对象,发现参与血吸虫生长、发育等关键分子。
基本信息
- 中文名
程国锋
- 国籍
中国
- 民族
汉族
主要贡献
论文发表
A. SCI期刊 (*Corresponding author)(1) Cheng G*, Luo R, Hu C, Lin J, Bai Z, Zhang B, Wang H. TiO2-based phosphoproteomic analysis of schistosomes: characterization of phosphorylated proteins in the different stages and sex of Schistosoma japonicum. J Proteome Res. 2013 Feb 1;12(2):729-42. (2011 SCI IF=5.11).(2) Luo R, Zhou C, Shi Y, Zhao J, Cheng G*. Molecular characterization of a cytokine-induced apoptosis inhibitor from Schistosoma japonicum. Parasitol Res. 2012 Dec;111(6):2317-24. (2011 SCI IF=2.149).(3) Cheng G* and Jin YX. microRNAs: Potentially Important Regulators for Schistosome Development and Therapeutic Targets against Schistosomiasis. Parasitology. 2012 Apr;139(5):669-79. (2011 SCI IF=2.96).(4) Luo R, Zhou C, Lin J, Yang D, Shi Y, Cheng G*. Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach. J Proteomics. 2012, 75(3):868-77. (2010 SCI IF=5.047)(5) Chen J, Yang Y, Guo S, Peng J, Liu Z, Li J, Lin J*, Cheng G*. Molecular cloning and expression profiles of Argonaute proteins in Schistosoma japonicum. Parasitol Res. 2010;107(4):889-99. (2010 SCI IF=1.812)(6) Peng J, Yang Y, Feng X, Cheng G*, Lin J*. Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum. Parasitol Res. 2010;106(4):967-76. (2010 SCI IF=1.812)(7) Cheng G, Fu Z, Lin J, Shi Y, Zhou Y, Jin Y, Cai Y. In vitro and in vivo evaluation of small interference RNA-mediated gynaecophoral canal protein silencing in Schistosoma japonicum. J Gene Med. 2009;11(5):412-21. (2009 SCI IF=2.986)(8) Cheng G, Zhu L, Mahato RI. Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets. Mol Pharm. 2008;5(6):1093-102. (2008 SCI IF=4.565)(9) Chen Y, Cheng G, Mahato RI. RNAi for treating hepatitis B viral infection. Pharm Res. 2008;25(1):72-86. (2008 SCI IF=4.024)(10) Cheng G, Davis RE. An improved and secreted luciferase reporter for schistosomes. Mol Biochem Parasitol. 2007;155(2):167-71. (2007 SCI IF=2.896) 【Selected by Faculty 1000 biology】(11) Cheng G, Cohen L, Mikhli C, Jankowska-Anyszka M, Stepinski J, Darzynkiewicz E, Davis RE. In vivo translation and stability of trans-spliced mRNAs in nematode embryos. Mol Biochem Parasitol. 2007;153(2):95-106. (2007 SCI IF=2.896)(12) Cheng G, Cohen L, Ndegwa D, Davis RE. The flatworm spliced leader 3'-terminal AUG as a translation initiator methionine. J Biol Chem. 2006 13;281(2):733-43. (2006 SCI IF=5.808)(13) Cheng GF, Lin JJ, Shi Y, Jin YX, Fu ZQ, Jin YM, Zhou YC, Cai YM. Dose-dependent inhibition of gynecophoral canal protein gene expression in vitro in the schistosome (Schistosoma japonicum) by RNA interference. Acta Biochim Biophys Sin. 2005;37(6):386-90. (2005 SCI IF=0.505)(14) Cheng GF, Lin JJ, Feng XG, Fu ZQ, Jin YM, Yuan CX, Zhou YC, Cai YM. Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosoma japonicum after pairing. Proteomics. 2005;5(2):511-21. (2005 SCI IF=6.08)(15) 张亮, 程国锋, 付志强, 金亚美, 冯新港, 苑纯秀, 蔡幼民. 血吸虫新抗原基因SjMF4的克隆、表达及功能分析. 生物化学与生物物理学报, 2003,35(12):1099-1104. (2003 SCI IF=0.524)B. 编著(16) Cheng G, Danquah M and Mahato RI (2009) MicroRNAs as therapeutic targets for cancer. In: Lu Y and Mahato RI (eds) Pharmaceutical Perspectives of Cancer Therapeutics (ISBN: 978-1-4419-0130-9) Springer, New York, NY. pp441-474.
科研经历
2001.2-2005.1 中国农业科学院上海家畜寄生虫病研究所,博士研究生;2005.4-2007.4 University of Colorado School of Medicine,博士后;2007.4-2008.8 The University of Tennessee Health Science Center,研究助理;2008.8-至今 中国农业科学院上海兽医研究所,研究员,课题组长。
荣誉记录
2006年获上海明治生命科学奖科学奖;2007年获全国百篇优秀博士论文提名;2008年获中国农业科学院科学技术成果奖二等奖(第三完成人);2008年获上海市科技进步奖二等奖(第三完成人);2009年获上海市领军人才后备队培养计划(闵行领军人才);2009年获上海市人才发展资金资助;2010年获上海市浦江人才称号并获资助。